The Online Collaborative Research Environment (OnCore), is a clinical trial management system (CTMS) that enables the management of research, financial, safety, regulatory, biospecimen, and operational data in one location.  It is the system in use at the University of California, San Francisco for Coverage Analysis. All clinical trials or research studies requiring Coverage Analysis must have a record in OnCore and all study Patient/Subjects must be enrolled in OnCore.

OnCore is managed and maintained by the UCSF OnCore Team, which works closely with study teams interested in incorporating OnCore into their workflows for more efficient clinical research operations and centralized data management.  UCSF supports all of OnCore’s modules to provide a variety of data solutions and operations management tools for clinical research teams. 

If you have questions about UCSF OnCore services, please contact the OnCore Helpdesk at [email protected] or 415-502-2962.


Who do I contact for help?

The Office of Clinical Trial Activation is committed to assisting study teams; here are options for getting help with questions you may have.


Patient/Subject Enrollment in OnCore

Starting May 7, 2018, UCSF began enrolling and tracking study subject visits in a single clinical trials management system, OnCore, for all clinical trials that bill through APeX. This created the following changes in study team workflows:

1. All study Patients/Subjects need to be Enrolled in OnCore; study teams are no longer able to enroll subjects in APeX.  To Enroll a Patient/Subject in OnCore:

  • Add Patient/Subject to the Trial
  • Give active status of Consented
  • Update Patient/Subject's On Study, On Arm, and On Treatment dates
  • Confirm Patient/Subjects Calendar dates

    Click here for a summary of the required fields to enroll a subject in OnCore.

2. It is very important to link Research Patient encounter(s) in APeX; here is a tip sheet to help with this process.

3. Now you can:

  • Place orders in APeX
  • Track Study Visits in OnCore